SLC22A7 Antikörper

Produktnummer ABIN289967

Produktdetails anti-SLC22A7 Antikörper

Target: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT2 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 2 (OAT2)

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry 5ug/ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC22A7

Target: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Andere Bezeichnung: Organic Anion Transporter 2 (OAT2) (SLC22A7 Produkte)

Synonyme: NLT antikoerper, OAT2 antikoerper, Oat2 antikoerper, oat2 antikoerper, nlt antikoerper, slc22a7 antikoerper, im:6901703 antikoerper, im:7155670 antikoerper, oat2a antikoerper, zgc:162334 antikoerper, oat2e antikoerper, slc22a7b antikoerper, zgc:63958 antikoerper, solute carrier family 22 member 7 antikoerper, solute carrier family 22 (organic anion transporter), member 7 antikoerper, solute carrier family 22 (organic anion transporter), member 7 L homeolog antikoerper, solute carrier family 22 (organic anion transporter), member 7a antikoerper, solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1 antikoerper, SLC22A7 antikoerper, Slc22a7 antikoerper, slc22a7.L antikoerper, slc22a7a antikoerper, slc22a7b.1 antikoerper

Hintergrund: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Organic anion transporter 2 (OAT2) is predicted 12 putative membrane-spanning protein, and which is expressed predominantly in the liver and only weakly in the kidney. OAT2 mediates the Na+-independent transport of organic anions, such as salicylate, and also mediates the transport of prostaglandin E2 (PGE2),methotrexate, acetylsalicylate and PAH (p-aminohippurate).This has been proved to be useful for immunohistochemistry .