SLC25A14 Antikörper

Produktnummer ABIN286000

Produktdetails anti-SLC25A14 Antikörper

Target: SLC25A14 (Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC25A14 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität (Details): UCP5 may be alternatively spliced to produced at least 3 transcripts: UCP5L has a unique 22-aa unique N-terminal sequence, UCP5S is missing 3 aa (23-25 aa) and UCP5S has 31 aa insertion between TM II-IV. The UCP5 sequence is conserved in all 3 isoforms in rat and mouse UCP5. It is 94 % conserved in human UCP5/BMCP1. UCP5 has no appreciable homology with UCP1-4.

Aufreinigung: Affinity chromatography purified

Immunogen: UCP5 antibody was raised in rabbit using a 16 amino acid peptide from rat UCP5 as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000-1:100,000, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

UCP5Blocking Peptide, catalog no. 30R-AU004, is also available for use as a blocking control in assays to test for specificity of thisUCP5 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS to a concentration of 1 mg/mL. Do not dilute further until ready to use.

Konzentration: Lot specific

Buffer: Affinity purified IgG lyophilized from PBS with 0.1 % BSA, and 0.05 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu SLC25A14

Target: SLC25A14 (Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))

Andere Bezeichnung: UCP5 (SLC25A14 Produkte)

Synonyme: ATPUMP5 antikoerper, DIC1 antikoerper, DICARBOXYLATE CARRIER 1 antikoerper, F14M13.10 antikoerper, F14M13_10 antikoerper, PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5 antikoerper, uncoupling protein 5 antikoerper, zgc:55596 antikoerper, BMCP1 antikoerper, UCP5 antikoerper, BMCP-1 antikoerper, Ucp5 antikoerper, UCP5L antikoerper, UCP5S antikoerper, Bmcp1 antikoerper, solute carrier family 25 member 14 antikoerper, uncoupling protein 5 antikoerper, solute carrier family 25 (mitochondrial carrier, brain), member 14 antikoerper, SLC25A14 antikoerper, UCP5 antikoerper, slc25a14 antikoerper, Slc25a14 antikoerper

Hintergrund: Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. UCP5 or Brain Mitochondrial Carrier Protein 1 or BMCP1 (human 322 aa, chromosome Xq24, ~35% identity with UCP1-3) is mainly expressed in the brain and testis.

Pathways: Proton Transport