AVPV1a Antikörper

Produktnummer ABIN285663

Produktdetails

Target: AVPV1a

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Kreuzreaktivität (Details): This 19 aa rat immunogenic peptide has 100 % sequence homology with rat AVP1a receptors (394, 395, and 424 aa), 84 % with mouse, 68 % with human, and 52 % with sheep AVR-V1a receptors. However, no significant similarity is seen with AVP V1b or V2 or V3 receptors.

Aufreinigung: Affinity chromatography purified

Immunogen: AVPV1 a antibody was raised in rabbit using 11 a peptide of rat AVP-VIa receptor. as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000-1:100,000, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS to a concentration of 1 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 0.1 % BSA.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen

Canal, Wilkinson, Cooper, Wraith, Wynn, Bigger: "Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB." in: Behavioural brain research, Vol. 209, Issue 2, pp. 212-20, (2010) (PubMed).

Antigendetails

Target: AVPV1a

Hintergrund: Vasopressin receptors are members of the G-protein coupled receptors with putative 7 transmembrane domains. The sizes of various AVP receptors are V1a (rat, 424 AA, human, 418 AA), V1b (rat, 421 AA, human, 424 AA), V2 (rat, 371 AA, human 371 AA).