PTGS1 Antikörper (C-Term)

Produktnummer ABIN2855874

Produktdetails anti-PTGS1 Antikörper

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to COX1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase))
COX1 antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COX1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Andere Bezeichnung: prostaglandin-endoperoxide synthase 1 (PTGS1 Produkte)

Synonyme: COX-1 antikoerper, cox-1 antikoerper, PTGS1 antikoerper, Ptgs1 antikoerper, COX1 antikoerper, Cox-1 antikoerper, Cox-3 antikoerper, PGHS-1 antikoerper, PHS 1 antikoerper, Pghs1 antikoerper, Cox1 antikoerper, Cox3 antikoerper, cox1 antikoerper, zCOX-1 antikoerper, COX3 antikoerper, PCOX1 antikoerper, PES-1 antikoerper, PGG/HS antikoerper, PGHS1 antikoerper, PHS1 antikoerper, PTGHS antikoerper, COX-3 antikoerper, prostaglandin-endoperoxide synthase 1 antikoerper, cyclooxygenase-1 antikoerper, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antikoerper, prostaglandin-endoperoxide synthase 1 S homeolog antikoerper, PTGS1 antikoerper, cox-1 antikoerper, Ptgs1 antikoerper, ptgs1 antikoerper, ptgs1.S antikoerper

Hintergrund: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Cellular Localization: Microsome membrane, Peripheral membrane protein , Endoplasmic reticulum membrane, Peripheral membrane protein

Molekulargewicht: 69 kDa

Gen-ID: 5742

UniProt: P23219