Haptoglobin Antikörper
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- Target Alle Haptoglobin (HP) Antikörper anzeigen
- Haptoglobin (HP)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Haptoglobin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
Haptoglobin antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Haptoglobin. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product HP Primärantikörper
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- Applikationshinweise
- WB: 1:5000-1:30000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Haptoglobin (HP)
- Andere Bezeichnung
- haptoglobin (HP Produkte)
- Synonyme
- HP antikoerper, wu:fb64e01 antikoerper, BP antikoerper, HP2ALPHA2 antikoerper, HPA1S antikoerper, HP-1 antikoerper, HPR antikoerper, Zonulin antikoerper, haptoglobin antikoerper, haptoglobin-like antikoerper, HP antikoerper, hp antikoerper, Hp antikoerper, LOC479668 antikoerper, LOC101102413 antikoerper
- Hintergrund
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This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Secreted - Molekulargewicht
- 45 kDa
- Gen-ID
- 3240
- UniProt
- P00738
- Pathways
- Transition Metal Ion Homeostasis
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