AP2B1 Antikörper (Internal Region)

Produktnummer ABIN2855154

Produktdetails anti-AP2B1 Antikörper

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (100 %)

Produktmerkmale: Rabbit polyclonal antibody to beta-Adaptin (adaptor-related protein complex 1, beta 1 subunit)
beta-Adaptin antibody [N3C1], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human beta-Adaptin. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.55 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu AP2B1

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Andere Bezeichnung: beta-Adaptin (AP2B1 Produkte)

Synonyme: 5-HT(2B) antikoerper, 5-HT2B antikoerper, ADTB2 antikoerper, AP105B antikoerper, AP2-BETA antikoerper, CLAPB1 antikoerper, 1300012O03Rik antikoerper, AI788979 antikoerper, fa16e07 antikoerper, wu:fa16c06 antikoerper, wu:fa16e07 antikoerper, wu:fc18c08 antikoerper, zgc:55659 antikoerper, 5-hydroxytryptamine receptor 2B antikoerper, adaptor related protein complex 2 beta 1 subunit antikoerper, adaptor-related protein complex 2, beta 1 subunit antikoerper, adaptor related protein complex 2 beta 1 subunit L homeolog antikoerper, HTR2B antikoerper, AP2B1 antikoerper, Ap2b1 antikoerper, ap2b1 antikoerper, ap2b1.L antikoerper

Hintergrund: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist.

Cellular Localization: Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle membrane

Molekulargewicht: 105 kDa

Gen-ID: 162

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation