STRA6 Antikörper (C-Term)

Produktnummer ABIN653383

Produktdetails anti-STRA6 Antikörper

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Bindungsspezifität: AA 586-614, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STRA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-614 AA from the C-terminal region of human STRA6.

Klon: RB25359

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
WB = 1:1000, IHC (p) = 1:50-100
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Details zu STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Andere Bezeichnung: STRA6 (STRA6 Produkte)

Synonyme: MCOPCB8 antikoerper, MCOPS9 antikoerper, AI891933 antikoerper, RGD1307551 antikoerper, STRA6 antikoerper, im:7151282 antikoerper, wu:fc51h06 antikoerper, zgc:136689 antikoerper, mcops9 antikoerper, pp14296 antikoerper, stimulated by retinoic acid 6 antikoerper, stimulated by retinoic acid gene 6 antikoerper, stimulated by retinoic acid gene 6 homolog (mouse) antikoerper, STRA6 antikoerper, Stra6 antikoerper, stra6 antikoerper

Hintergrund: Function
May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity).

Cellular Location
Cell membrane, Multi-pass membrane protein (Potential)

Tissue Location
Broad expression. In adult eye expressed in sclera, retina, retinal pigment epithelium, and trabecular meshwork but not in choroid and iris

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, UNQ3126/PRO10282/PRO19578, PP14296, STRA6

Molekulargewicht: 73503 Da

Gen-ID: 64220

UniProt: Q9BX79

Pathways: Feeding Behaviour