GLIPR2 Antikörper (AA 51-154) (Alexa Fluor 594)

Produktnummer ABIN2813775

Produktdetails anti-GLIPR2 Antikörper (Alexa Fluor 594)

Target: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Bindungsspezifität: AA 51-154

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIPR2 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLIPR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GLIPR2

Target: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Andere Bezeichnung: GLIPR2 (GLIPR2 Produkte)

Synonyme: fd05a10 antikoerper, im:6795575 antikoerper, wu:fd05a10 antikoerper, si:dkey-2n12.1 antikoerper, C9orf19 antikoerper, GAPR-1 antikoerper, GAPR1 antikoerper, 5730414A08Rik antikoerper, C77180 antikoerper, C8H9ORF19 antikoerper, GLI pathogenesis-related 2 antikoerper, GLI pathogenesis related 2 antikoerper, glipr2 antikoerper, GLIPR2 antikoerper, Glipr2 antikoerper

Hintergrund:

Synonyms: GAPR 1, GAPR-1, GAPR1_HUMAN, GLI pathogenesis related 2, Glioma pathogenesis related protein 2, Glioma pathogenesis-related protein 2, GliPR 2, GLIPR2, Golgi associated plant pathogenesis related protein 1, Golgi associated PR 1 protein, Golgi-associated plant pathogenesis-related protein 1, Golgi-associated PR-1 protein, OTTMUSP00000007558, RP11-421H8.5, RP23-209M8.2, C77180, 5730414A08Rik, C9orf19.

Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.