FOXO4/ FOXO1/ (pSer197), (pSer256) Antikörper (Alexa Fluor 594)

Produktnummer ABIN2813371

Produktdetails

Target: FOXO4/ FOXO1/

Bindungsspezifität: pSer197, pSer256

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 594

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Ser197

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: FOXO4/ FOXO1/

Hintergrund:

Synonyms: FOXO4 phospho S197, p-FOXO4 phospho S197, AFXSer197, Fork head domain transcription factor AFX1, AFX, AFX1, Afxh, ALL1-fused gene from X chromosome, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, FOXO 4, Mixed lineage leukemia, translocated to, 7, MLLT7, Myeloid lymphoid or mixed lineage leukemia translocated to 7, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7, Putative fork head domain transcription factor AFX1, FOXO1 Phospho-Ser256, Forkhead box protein O1 Phospho Ser256, FKHR Phospho-Ser256, FOXO1A Phospho-Ser256.

Background: These genes encode a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. Multiple transcript variants encoding different isoforms have been found for these genes. Both function as transcription factors involved in the regulation of the insulin signaling pathway.

Gen-ID: 4303

UniProt: Q9WVH3