CITED1 Antikörper (AA 150-193) (Alexa Fluor 594)
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- Target Alle CITED1 Antikörper anzeigen
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
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Bindungsspezifität
- AA 150-193
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CITED1 Antikörper ist konjugiert mit Alexa Fluor 594
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CITED1
- Isotyp
- IgG
- Top Product
- Discover our top product CITED1 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
- Andere Bezeichnung
- CITED1 (CITED1 Produkte)
- Synonyme
- cited1 antikoerper, fi05d05 antikoerper, CITED1 antikoerper, MSG1 antikoerper, AI316840 antikoerper, AU019144 antikoerper, Msg1 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antikoerper, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antikoerper, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antikoerper, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antikoerper, cited1 antikoerper, CITED1 antikoerper, Cited1 antikoerper
- Hintergrund
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Synonyms: MSG1, Cbp/p300-interacting transactivator 1, Melanocyte-specific protein 1, CITED1
Background: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
- Gen-ID
- 4435
- UniProt
- Q99966
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