Membralin Antikörper (AA 161-260) (Alexa Fluor 594)

Produktnummer ABIN2804142

Produktdetails anti-Membralin Antikörper (Alexa Fluor 594)

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Bindungsspezifität: AA 161-260

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Membralin Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Zebrafisch (Danio rerio)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Membralin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Membralin

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Andere Bezeichnung: Membralin/C19orf6 (TMEM259 Produkte)

Synonyme: ASBABP1 antikoerper, C19orf6 antikoerper, MBRL antikoerper, MEMBRALIN antikoerper, R32184_3 antikoerper, C28H19orf6 antikoerper, c19orf6 antikoerper, AC087114.7gm12 antikoerper, AC087114.7gm2 antikoerper, ORF61 antikoerper, mFLJ00277 antikoerper, Mbrl antikoerper, RGD1311136 antikoerper, transmembrane protein 259 antikoerper, transmembrane protein 259 L homeolog antikoerper, TMEM259 antikoerper, tmem259.L antikoerper, Tmem259 antikoerper

Hintergrund:

Synonyms: ASBABP1, C19orf6, MGC4022, R32184_3, aspecic BCL2 ARE-binding protein 1, C19orf6, chromosome 19 open reading frame 6, MBRL, MBRL_HUMAN.

Background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.