CYP2A6 Antikörper

Produktnummer ABIN1944821

Produktdetails anti-CYP2A6 Antikörper

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-CYP2A6 Antikörper (ABIN1944821)

Yamano, Tatsuno, Gonzalez: "The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes." in: Biochemistry, Vol. 29, Issue 5, pp. 1322-9, (1990) (PubMed).

Miles, Bickmore, Brook, McLaren, Meehan, Wolf: "Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity." in: Nucleic acids research, Vol. 17, Issue 8, pp. 2907-17, (1989) (PubMed).

Yamano, Nagata, Yamazoe, Kato, Gelboin, Gonzalez: "cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)." in: Nucleic acids research, Vol. 17, Issue 12, pp. 4888, (1989) (PubMed).

Details zu CYP2A6

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Andere Bezeichnung: Cytochrome P450 2A6 (CYP2A6 Produkte)

Synonyme: CPA6 antikoerper, CYP2A antikoerper, CYP2A3 antikoerper, CYPIIA6 antikoerper, P450C2A antikoerper, P450PB antikoerper, cyp2a6 antikoerper, cytochrome P450 family 2 subfamily A member 6 antikoerper, cytochrome P450 2A6 antikoerper, cytochrome P450 family 2 subfamily A member 6 L homeolog antikoerper, CYP2A6 antikoerper, cyp2a6.L antikoerper

Hintergrund: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity.

Molekulargewicht: 56501 Da

Gen-ID: 1548

UniProt: P11509