PCDHa8 Antikörper (C-Term)

Produktnummer ABIN2797569

Produktdetails anti-PCDHa8 Antikörper

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Bindungsspezifität: AA 773-800, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHa8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: Rabbit Anti-Human PCDHA8 (C-term) Antibody

Immunogen: This PCDHA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-800 amino acids from the C-terminal region of human PCDHA8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50PCDHA8 Antibody (C-term) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PCDHa8

Target: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Andere Bezeichnung: PCDHA8 (PCDHa8 Produkte)

Synonyme: PCDH-ALPHA8 antikoerper, protocadherin alpha 8 antikoerper, PCDHA8 antikoerper, Pcdha8 antikoerper

Hintergrund:

Target Description: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Symbol: PCDHA8

Molekulargewicht: 103051 Da

Gen-ID: 56140

UniProt: Q9Y5H6