EXOSC6 Antikörper (N-Term)

Produktnummer ABIN2795600

Produktdetails anti-EXOSC6 Antikörper

Target: EXOSC6 (Exosome Component 6 (EXOSC6))

Bindungsspezifität: AA 12-38, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human EXOSC6 (N-term) Antibody

Immunogen: This EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000EXOSC6 Antibody (N-term) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu EXOSC6

Target: EXOSC6 (Exosome Component 6 (EXOSC6))

Andere Bezeichnung: EXOSC6 (EXOSC6 Produkte)

Synonyme: exosc6 antikoerper, RAR-gamma antikoerper, id:ibd1130 antikoerper, wu:fe17d05 antikoerper, zgc:110071 antikoerper, EAP4 antikoerper, MTR3 antikoerper, Mtr3p antikoerper, hMtr3p antikoerper, p11 antikoerper, 2610510N21Rik antikoerper, C76919 antikoerper, Mtr3 antikoerper, exosome component 6 antikoerper, EXOSC6 antikoerper, exosc6 antikoerper, CpipJ_CPIJ018071 antikoerper, Exosc6 antikoerper

Hintergrund:

Target Description: This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

Gene Symbol: EXOSC6

Molekulargewicht: 28235 Da

Gen-ID: 118460

UniProt: Q5RKV6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response