GPR37 Antikörper (C-Term)

Produktnummer ABIN2794908

Produktdetails anti-GPR37 Antikörper

Target: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Bindungsspezifität: AA 217-246, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Human Pael-R (GPR37) (C-term) Antibody

Immunogen: This Pael-R (GPR37) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human Pael-R (GPR37).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-Pael-R (GPR37) Antibody (C-term) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu GPR37

Target: GPR37 (G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) (GPR37))

Andere Bezeichnung: Pael-R (GPR37 Produkte)

Synonyme: ACCA antikoerper, EDNRBL antikoerper, PAELR antikoerper, hET(B)R-LP antikoerper, AI848630 antikoerper, Pael-R antikoerper, Ednrbl antikoerper, G protein-coupled receptor 3 antikoerper, G protein-coupled receptor 37 antikoerper, GPR3 antikoerper, GPR37 antikoerper, Gpr37 antikoerper

Hintergrund:

Target Description: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known, however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons, coexpression of Parkin degrades Pael-R and suppresses its toxicity.

Gene Symbol: GPR37

Molekulargewicht: 67114 Da

Gen-ID: 2861

UniProt: O15354