ABCC5 Antikörper (Center)

Produktnummer ABIN2793440

Produktdetails anti-ABCC5 Antikörper

Target: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Bindungsspezifität: AA 625-652, Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: Rabbit Anti-Human ABCC5 (Center) Antibody

Immunogen: This ABCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 625-652 amino acids from the Central region of human ABCC5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of ABCC5 Antibody (Center) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ABCC5

Target: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Andere Bezeichnung: ABCC5 (ABCC5 Produkte)

Synonyme: ABC33 antikoerper, EST277145 antikoerper, MOAT-C antikoerper, MOATC antikoerper, MRP5 antikoerper, SMRP antikoerper, pABC11 antikoerper, 2900011L11Rik antikoerper, AI132311 antikoerper, Abcc5a antikoerper, Abcc5b antikoerper, Mrp5 antikoerper, abc33 antikoerper, abcc5 antikoerper, moat-c antikoerper, moatc antikoerper, mrp5 antikoerper, pabc11 antikoerper, smrp antikoerper, ATP binding cassette subfamily C member 5 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 5 antikoerper, ATP binding cassette subfamily C member 5 L homeolog antikoerper, ABCC5 antikoerper, Abcc5 antikoerper, abcc5.L antikoerper

Hintergrund:

Target Description: ABCC5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs,6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients.

Gene Symbol: ABCC5

Molekulargewicht: 160660 Da

Gen-ID: 10057

UniProt: O15440

Pathways: Glycosaminoglycan Metabolic Process