GABPA Antikörper (C-Term)

Produktnummer ABIN2792606

Produktdetails anti-GABPA Antikörper

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KWGQRKNKPT MNYEKLSRAL RYYYDGDMIC KVQGKRFVYK FVCDLKTLIG

Kreuzreaktivität: Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GABPA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GABPA Antibody Titration: 0.5-1.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 454 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Andere Bezeichnung: GABPA (GABPA Produkte)

Synonyme: gabpa-A antikoerper, XrpFI antikoerper, X-alpha1 antikoerper, GABPA antikoerper, nft2 antikoerper, nrf2 antikoerper, nrf2a antikoerper, e4tf1a antikoerper, e4tf1-60 antikoerper, Nrf-2alpha antikoerper, Nrf2a antikoerper, E4TF1-60 antikoerper, E4TF1A antikoerper, NFT2 antikoerper, NRF2 antikoerper, NRF2A antikoerper, RCH04A07 antikoerper, GABPalpha antikoerper, e4tf antikoerper, wu:fc12d11 antikoerper, GA binding protein transcription factor alpha subunit S homeolog antikoerper, GA binding protein transcription factor alpha subunit antikoerper, GA binding protein transcription factor, alpha subunit antikoerper, GA binding protein transcription factor alpha subunit L homeolog antikoerper, GA repeat binding protein, alpha antikoerper, gabpa.S antikoerper, GABPA antikoerper, gabpa antikoerper, Gabpa antikoerper, gabpa.L antikoerper

Hintergrund: GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
Alias Symbols: NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07
Protein Interaction Partner: UBC, NCOA7, KCTD12, TSEN34, DIABLO, CUTC, RAB3GAP2, LIMCH1, RAB3GAP1, GNE, KPNA1, YY1, GABPB1, PINX1, APP, KEAP1, SUMO2, HDAC1, EP300, SP3, CREBBP, HCFC1, SP1, ATF1, MED1,
Protein Size: 454

Molekulargewicht: 51 kDa

Gen-ID: 2551

NCBI Accession: NM_002040, NP_002031

UniProt: Q06546

Pathways: Myometrial Relaxation and Contraction