SOX9 Antikörper (N-Term)

Produktnummer ABIN184299

Produktdetails anti-SOX9 Antikörper

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PCPSGSGSDT ENTRPQENTF PKGEPDLKKE SEEDKFPVCI REAVSQVLKG

Kreuzreaktivität: Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX9

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-SOX9 Antibody Titration: 2.5 µg/mL
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 509 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9 (SOX9 Produkte)

Synonyme: CMD1 antikoerper, CMPD1 antikoerper, SRA1 antikoerper, LOC100227849 antikoerper, 2010306G03Rik antikoerper, AV220920 antikoerper, mKIAA4243 antikoerper, SOX-9 antikoerper, cmd1 antikoerper, cmpd1 antikoerper, sox-9 antikoerper, sox9 antikoerper, sox9-a antikoerper, sox9-b antikoerper, sox9b antikoerper, sra1 antikoerper, SRY-box 9 antikoerper, transcription factor SOX-9 antikoerper, SRY (sex determining region Y)-box 9 antikoerper, SRY box 9 antikoerper, SRY-box 9 L homeolog antikoerper, SOX9 antikoerper, LOC100227849 antikoerper, Sox9 antikoerper, sox9.L antikoerper

Hintergrund: SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Alias Symbols: CMD1, SRA1, CMPD1
Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
Protein Size: 509

Molekulargewicht: 56 kDa

Gen-ID: 6662

NCBI Accession: NM_000346, NP_000337

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development