CXCR6 Antikörper (N-Term)

Produktnummer ABIN487291

Produktdetails anti-CXCR6 Antikörper

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AEHDYHEDYG FSSFNDSSQE EHQDFLQFSK VFLPCMYLVV FVCGLVGNSL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CXCR6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 342 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Andere Bezeichnung: CXCR6 (CXCR6 Produkte)

Synonyme: BONZO antikoerper, CD186 antikoerper, STRL33 antikoerper, TYMSTR antikoerper, BB217514 antikoerper, C-X-C motif chemokine receptor 6 antikoerper, chemokine (C-X-C motif) receptor 6 L homeolog antikoerper, chemokine (C-X-C motif) receptor 6 antikoerper, CXCR6 antikoerper, cxcr6.L antikoerper, Cxcr6 antikoerper

Hintergrund: CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.
Alias Symbols: BONZO, CD186, STRL33, TYMSTR
Protein Interaction Partner: CXCL16,
Protein Size: 342

Molekulargewicht: 39 kDa

Gen-ID: 10663

NCBI Accession: NM_006564, NP_006555

UniProt: O00574