FKBP1A Antikörper (N-Term)
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- Target Alle FKBP1A Antikörper anzeigen
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FKBP1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GQTCVVHYTG MLEDGKKFDS SRDRNKPFKF MLGKQEVIRG WEEGVAQMSV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FKBP1A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product FKBP1A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 108 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- Andere Bezeichnung
- FKBP1A (FKBP1A Produkte)
- Synonyme
- 12kDa antikoerper, FKBP12 antikoerper, FKBP12-T1 antikoerper, FKBP12-T2 antikoerper, Fkbp antikoerper, Fkbp1 antikoerper, mFKBP1 antikoerper, mFKBP12 antikoerper, FKBP-12 antikoerper, FKBP-1A antikoerper, FKBP1 antikoerper, Rotamase antikoerper, Fkbp12 antikoerper, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antikoerper, ATFKBP12 antikoerper, FK506-binding protein 12 antikoerper, IMMUNOPHILIN antikoerper, MSJ1.19 antikoerper, MSJ1_19 antikoerper, PKC12 antikoerper, PKCI2 antikoerper, PPIASE antikoerper, FKBP1B antikoerper, Fkbp2 antikoerper, fj02g10 antikoerper, zgc:73373 antikoerper, wu:fj02g10 antikoerper, FKBP1A antikoerper, Bmfkbp13 antikoerper, zgc:103752 antikoerper, FK506 binding protein 1a antikoerper, FK506 binding protein 1A antikoerper, FK506-binding protein antikoerper, FK506-binding protein 12 antikoerper, FK506 binding protein 1Aa antikoerper, FK506 binding protein 1C antikoerper, FK506-binding protein 59 antikoerper, FK506 binding protein like antikoerper, FK506 binding protein 1A L homeolog antikoerper, FK506 binding protein 1Ab antikoerper, Fkbp1a antikoerper, FKBP1A antikoerper, Fkbp12 antikoerper, FKBP12 antikoerper, fkbp1aa antikoerper, FKBP1C antikoerper, EHI_180160 antikoerper, LOC5573443 antikoerper, Fkbp13 antikoerper, FKBPL antikoerper, fkbp1a.L antikoerper, fkbp1ab antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Alias Symbols: FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PKCI2, PPIASE, FKBP-1A
Protein Interaction Partner: AHSP, SF3B4, MID1, MTOR, TGFB1, UBC, BAG3, ACVRL1, BARD1, ZPR1, APP, ELAVL1, ACVR1B, SMAD7, TRPC3, FKBP4, TGFB1I1, GLMN, PPP3R1, YY1, TGFBR1, FKBP1A, RYR3, RYR1, ITPR1, DHFR, PPP3CA, BMPR1A, RPTOR,
Protein Size: 108 - Molekulargewicht
- 12 kDa
- Gen-ID
- 2280
- NCBI Accession
- NM_000801, NP_000792
- UniProt
- P62942
- Pathways
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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