NDUFA1 Antikörper (N-Term)

Produktnummer ABIN2789932

Produktdetails anti-NDUFA1 Antikörper

Target: NDUFA1 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VMGVCLLIPG LATAYIHRFT NGGKEKRVAH FGYHWSLMER DRRISGVDRY

Homologie: Cow: 85%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 79%, Rat: 92%, Sheep: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NDUFA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 70 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NDUFA1

Target: NDUFA1 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1))

Andere Bezeichnung: NDUFA1 (NDUFA1 Produkte)

Synonyme: 1810049F12Rik antikoerper, MWFE antikoerper, RGD1560955 antikoerper, CI-MWFE antikoerper, ZNF183 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 antikoerper, NADH:ubiquinone oxidoreductase subunit A1 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa antikoerper, Ndufa1 antikoerper, NDUFA1 antikoerper

Hintergrund: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Alias Symbols: CI-MWFE, MWFE, ZNF183
Protein Interaction Partner: TRIM63, TRIM55, UBC, GOLGB1,
Protein Size: 70

Molekulargewicht: 8 kDa

Gen-ID: 4694

NCBI Accession: NM_004541, NP_004532

UniProt: O15239