HRPT2 Antikörper (C-Term)
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- Target Alle HRPT2 (CDC73) Antikörper anzeigen
- HRPT2 (CDC73) (Parafibromin (CDC73))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HRPT2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KQGCQRENET LIQRRKDQMQ PGGTAISVTV PYRVVDQPLK LMPQDWDRVV
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CDC73. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product CDC73 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 531 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HRPT2 (CDC73) (Parafibromin (CDC73))
- Andere Bezeichnung
- CDC73 (CDC73 Produkte)
- Synonyme
- C1orf28 antikoerper, HPTJT antikoerper, HRPT2 antikoerper, HYX antikoerper, 8430414L16Rik antikoerper, BC027756 antikoerper, C130030P16Rik antikoerper, C81219 antikoerper, Hrpt2 antikoerper, hrpt2 antikoerper, zgc:63956 antikoerper, MGC108428 antikoerper, cdc73 antikoerper, LOC100222932 antikoerper, cell division cycle 73 antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antikoerper, parafibromin antikoerper, cell division cycle 73 S homeolog antikoerper, CDC73 antikoerper, Cdc73 antikoerper, cdc73 antikoerper, Tsp_03925 antikoerper, Tsp_04052 antikoerper, Tsp_04125 antikoerper, cdc73.S antikoerper
- Hintergrund
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This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Alias Symbols: C1orf28, FLJ23316, HPTJT, HRPT2, HYX
Protein Interaction Partner: CCDC155, FSD2, TSGA10, CEP70, VPS37B, MTUS2, UBC, TFCP2, GOLGA2, ALAS1, CIAO1, AURKB, GPRASP2, COG3, MYH14, MYL12A, ARFGEF2, NUP98, MYH9, CHUK, DNMT3B, DNMT3A, SOX2, BCL9L, PAF1, CTR9, TCF4, CTNNB1, LEO1, GTF2F1, SUV39H1, PTPN11, WDR61, HIST1H3A, RNF20, R
Protein Size: 531 - Molekulargewicht
- 58 kDa
- Gen-ID
- 79577
- NCBI Accession
- NM_024529, NP_078805
- UniProt
- Q6P1J9
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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