GADD45GIP1 Antikörper (Middle Region)
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- Target Alle GADD45GIP1 Antikörper anzeigen
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd, Schwein, Saccharomyces cerevisiae, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GADD45GIP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE
- Homologie
- Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product GADD45GIP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 222 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Andere Bezeichnung
- GADD45GIP1 (GADD45GIP1 Produkte)
- Synonyme
- si:dkey-194e13.6 antikoerper, CKBBP2 antikoerper, CRIF1 antikoerper, PLINP antikoerper, PLINP-1 antikoerper, PRG6 antikoerper, Plinp1 antikoerper, 2310040G17Rik antikoerper, AI425883 antikoerper, Crif1 antikoerper, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antikoerper, GADD45G interacting protein 1 antikoerper, gadd45gip1 antikoerper, GADD45GIP1 antikoerper, Gadd45gip1 antikoerper
- Hintergrund
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GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222 - Molekulargewicht
- 24 kDa
- Gen-ID
- 90480
- NCBI Accession
- NM_052850, NP_443082
- UniProt
- Q8TAE8
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