GADD45GIP1 Antikörper (Middle Region)

Produktnummer ABIN2789108

Produktdetails anti-GADD45GIP1 Antikörper

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd, Schwein, Saccharomyces cerevisiae, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45GIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE

Homologie: Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 222 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Andere Bezeichnung: GADD45GIP1 (GADD45GIP1 Produkte)

Synonyme: si:dkey-194e13.6 antikoerper, CKBBP2 antikoerper, CRIF1 antikoerper, PLINP antikoerper, PLINP-1 antikoerper, PRG6 antikoerper, Plinp1 antikoerper, 2310040G17Rik antikoerper, AI425883 antikoerper, Crif1 antikoerper, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antikoerper, GADD45G interacting protein 1 antikoerper, gadd45gip1 antikoerper, GADD45GIP1 antikoerper, Gadd45gip1 antikoerper

Hintergrund: GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222

Molekulargewicht: 24 kDa

Gen-ID: 90480

NCBI Accession: NM_052850, NP_443082

UniProt: Q8TAE8