HSD17B8 Antikörper (N-Term)

Produktnummer ABIN2789035

Produktdetails anti-HSD17B8 Antikörper

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD17B8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 261 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSD17B8

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Andere Bezeichnung: HSD17B8 (HSD17B8 Produkte)

Synonyme: KE6 antikoerper, fabgl antikoerper, zgc:112550 antikoerper, si:dz12f11.4 antikoerper, HKE6 antikoerper, FABGL antikoerper, ke6 antikoerper, fabg antikoerper, hke6 antikoerper, ring2 antikoerper, h2-ke6 antikoerper, d6s2245e antikoerper, D17H6S112E antikoerper, H-2Ke6 antikoerper, Hsd17b8 antikoerper, Ke-6 antikoerper, Ke6 antikoerper, Ring2 antikoerper, D6S2245E antikoerper, FABG antikoerper, H2-KE6 antikoerper, RING2 antikoerper, SDR30C1 antikoerper, dJ1033B10.9 antikoerper, Fabgl antikoerper, hydroxysteroid (17-beta) dehydrogenase 8 antikoerper, hydroxysteroid 17-beta dehydrogenase 8 antikoerper, H2-K region expressed gene 6 antikoerper, hsd17b8 antikoerper, HSD17B8 antikoerper, H2-Ke6 antikoerper, Hsd17b8 antikoerper

Hintergrund: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
Alias Symbols: D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9
Protein Interaction Partner: RAD21,
Protein Size: 261

Molekulargewicht: 29 kDa

Gen-ID: 7923

NCBI Accession: NM_014234, NP_055049

UniProt: Q92506

Pathways: Steroid Hormone Biosynthesis