MMACHC Antikörper (C-Term)

Produktnummer ABIN2788885

Produktdetails anti-MMACHC Antikörper

Target: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMACHC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IALLEGFNFH WRDWTYRDAV TPQERYSEEQ KAYFSTPPAQ RLALLGLAQP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MMACHC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 282 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MMACHC

Target: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Andere Bezeichnung: MMACHC (MMACHC Produkte)

Synonyme: cblC antikoerper, RP11-291L19.3 antikoerper, RGD1310806 antikoerper, 1810037K07Rik antikoerper, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria antikoerper, methylmalonic aciduria cblC type, with homocystinuria antikoerper, MMACHC antikoerper, Mmachc antikoerper

Hintergrund: The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Alias Symbols: DKFZp564I122, FLJ25671, RP11-291L19.3, cblC
Protein Interaction Partner: MMADHC, UBC,
Protein Size: 282

Molekulargewicht: 31 kDa

Gen-ID: 25974

NCBI Accession: NM_015506, NP_056321

UniProt: Q9Y4U1