TNFSF13 Antikörper (Middle Region)

Produktnummer ABIN2788639

Produktdetails anti-TNFSF13 Antikörper

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Schwein, Pferd, Kaninchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EQSSDALEAW ENGERSRKRR AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT

Homologie: Cow: 91%, Dog: 86%, Goat: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFSF13. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 250 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Andere Bezeichnung: TNFSF13 (TNFSF13 Produkte)

Synonyme: APRIL antikoerper, CD256 antikoerper, TALL-2 antikoerper, TALL2 antikoerper, TRDL-1 antikoerper, ZTNF2 antikoerper, 2310026N09Rik antikoerper, April antikoerper, Tall2 antikoerper, Trdl1 antikoerper, SLAN antikoerper, ANP32B antikoerper, april antikoerper, tnf13 antikoerper, TNLG7B antikoerper, TNF superfamily member 13 antikoerper, tumor necrosis factor (ligand) superfamily, member 13 antikoerper, acidic leucine-rich nuclear phosphoprotein 32 family member B antikoerper, TNFSF13 antikoerper, Tnfsf13 antikoerper, LOC494442 antikoerper, tnfsf13 antikoerper

Hintergrund: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Alias Symbols: APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand, ZTNF2, TALL-2
Protein Interaction Partner: CAMK1D, TNFRSF13B, TNFSF13B, TNFRSF14, TNFRSF11B, TNFRSF1A, SDC2, FURIN, FAS, TNFRSF17, TNFSF13,
Protein Size: 250

Molekulargewicht: 16 kDa

Gen-ID: 8741

NCBI Accession: NM_003808, NP_003799

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response