Angiotensin II Type 2 Receptor Antikörper (N-Term)

Produktnummer ABIN2788290

Produktdetails anti-Angiotensin II Type 2 Receptor Antikörper

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type 2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LHFGLVNISG NNESTLNCSQ KPSDKHLDAI PILYYIIFVI GFLVNIVVVT

Homologie: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AGTR2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGTR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Angiotensin II Type 2 Receptor

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Andere Bezeichnung: AGTR2 (AGTR2 Produkte)

Synonyme: AT2 antikoerper, ATGR2 antikoerper, MRX88 antikoerper, AI316812 antikoerper, AW107640 antikoerper, AT2-R antikoerper, AT2R antikoerper, AT₂R antikoerper, at2 antikoerper, zgc:113016 antikoerper, AGTR2 antikoerper, angiotensin II receptor type 2 antikoerper, angiotensin II receptor, type 2 antikoerper, AGTR2 antikoerper, Agtr2 antikoerper, agtr2 antikoerper

Hintergrund: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
Alias Symbols: AT2, ATGR2, MRX88
Protein Interaction Partner: ERBB2IP, TIMP3, SNTA1, ZBTB16, MTUS1, PIK3CB, ERBB3, GNAI3, GNAI2, ACE, AGT, AGTRAP,
Protein Size: 363

Molekulargewicht: 41 kDa

Gen-ID: 186

NCBI Accession: NM_000686, NP_000677

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones