MRGPRX2 Antikörper (Middle Region)

Produktnummer ABIN2788260

Produktdetails anti-MRGPRX2 Antikörper

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VCVLLWALSL LLSILEGKFC GFLFSDGDSG WCQTFDFITA AWLIFLFMVL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 330 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGPRX2 (MRGPRX2 Produkte)

Synonyme: MRGX2 antikoerper, G370024M05Rik antikoerper, MrgB10 antikoerper, Mrgprb10 antikoerper, MrgB1 antikoerper, Mrgprb1 antikoerper, MAS related GPR family member X2 antikoerper, MAS-related GPR, member X2 antikoerper, MRGPRX2 antikoerper, Mrgprx2 antikoerper

Hintergrund: MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Alias Symbols: MRGX2
Protein Interaction Partner: CORT,
Protein Size: 330

Molekulargewicht: 37 kDa

Gen-ID: 117194

NCBI Accession: NM_054030, NP_473371

UniProt: Q96LB1