PLEKHG2 Antikörper (Middle Region)

Produktnummer ABIN2788148

Produktdetails anti-PLEKHG2 Antikörper

Target: PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh), Maus, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLEKHG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DLTIPKHRHL LQAKNQEEKR LWIHCLQRLF FENHPASIPA KAKQVLLENS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PLEKHG2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLEKHG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1344 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLEKHG2

Target: PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))

Andere Bezeichnung: PLEKHG2 (PLEKHG2 Produkte)

Synonyme: ARHGEF42 antikoerper, CLG antikoerper, AI194308 antikoerper, Clg antikoerper, Cslg antikoerper, pleckstrin homology and RhoGEF domain containing G2 antikoerper, pleckstrin homology domain containing, family G (with RhoGef domain) member 2 antikoerper, PLEKHG2 antikoerper, Plekhg2 antikoerper

Hintergrund: PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
Alias Symbols: CLG, DKFZp667J2325, FLJ00018, FLJ22458, FLJ38638, ARHGEF42
Protein Interaction Partner: ACTN3, XRN1, APP, GNG2, GNB1, RAC1, RHOA, CDC42,
Protein Size: 1344

Molekulargewicht: 144 kDa

Gen-ID: 64857

NCBI Accession: NM_022835, NP_073746

UniProt: Q9H7P9