ERK2 Antikörper (C-Term)

Produktnummer ABIN2787870

Der Kaninchen Polyklonal Anti-ERK2-Antikörper wurde für WB validiert. Er ist geeignet, ERK2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Zebrafisch (Danio rerio), Meerschweinchen und Ziege zu detektieren.

Kurzübersicht für ERK2 Antikörper (C-Term) (ABIN2787870)

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Zebrafisch (Danio rerio), Meerschweinchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERK2 Antikörper

Bindungsspezifität: C-Term

Sequenz: PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAPK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 360 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Andere Bezeichnung: MAPK1

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Protein Interaction Partner: Eif4ebp1, ATF2, RPS6KA3, RAF1, PTGDR, MAP2K6, MAP2K1, MAPK3, HDAC6, TP53, NEDD8, DGCR8, HMGB1, NAV1, PDCD6IP, CEP350, MAPK12, RPS6KA2, MAPK1, PDE4D, MBP, KRAS, SQSTM1, CUEDC2, GAB2, BRAF, RPS6KA1, MAP2K4, MAP2K2, ELK1, NOXA1, TIAL1, GADD45A, MAP3K10, SMAD
Protein Size: 360

Molekulargewicht: 41 kDa

Gen-ID: 5594

NCBI Accession: NM_138957, NP_620407

UniProt: P28482

Pathways: MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteine