VPS36 Antikörper (N-Term)

Produktnummer ABIN2786923

Produktdetails anti-VPS36 Antikörper

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS36 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SNKEPGPFQS SKNSYIRLSF KEHGQIEFYR RLSEEMTQRR WETVPVSQSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Vps36. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 386 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VPS36

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Andere Bezeichnung: Vps36 (VPS36 Produkte)

Synonyme: C13orf9 antikoerper, EAP45 antikoerper, 1700010A24Rik antikoerper, 2210415M20Rik antikoerper, 2810408E15Rik antikoerper, Eap45 antikoerper, RGD1309754 antikoerper, fj33d07 antikoerper, wu:fj33d07 antikoerper, zgc:55965 antikoerper, MUG13.23 antikoerper, MUG13_23 antikoerper, VPS36 antikoerper, CG10711 antikoerper, Dmel\\CG10711 antikoerper, l(3)L5212 antikoerper, vps36 antikoerper, DDBDRAFT_0205116 antikoerper, DDBDRAFT_0234028 antikoerper, DDB_0205116 antikoerper, DDB_0234028 antikoerper, vacuolar protein sorting 36 homolog antikoerper, vacuolar protein sorting 36 antikoerper, vacuolar protein sorting-associated protein 36 antikoerper, vacuolar protein sorting 36 homolog (S. cerevisiae) antikoerper, EAP30/Vps36 family protein antikoerper, Vacuolar protein sorting 36 antikoerper, vacuolar protein sorting 36 homolog L homeolog antikoerper, vacuolar protein-sorting-associated protein 36 antikoerper, ESCRT II complex subunit Vps36 antikoerper, VPS36 antikoerper, Vps36 antikoerper, LACBIDRAFT_399634 antikoerper, vps36 antikoerper, AT5G04920 antikoerper, vps36.L antikoerper, PTRG_11114 antikoerper, MCYG_02556 antikoerper, MGYG_08257 antikoerper, TERG_05645 antikoerper, Tsp_04139 antikoerper

Hintergrund: Vps36 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
Alias Symbols: 1700010A24Rik, 2210415M20Rik, 2810408E15Rik, Eap45
Protein Interaction Partner: Ubc,
Protein Size: 386

Molekulargewicht: 42 kDa

Gen-ID: 70160

NCBI Accession: NM_027338, NP_081614

UniProt: Q91XD6