NDUFS1 Antikörper (Middle Region)

Produktnummer ABIN2786794

Produktdetails anti-NDUFS1 Antikörper

Target: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Ziege, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TPPGLAREDW KIIRALSEIA GMTLPYDTLD QVRNRLEEVS PNLVRYDDIE

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against NDUFS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDUFS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 727 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NDUFS1

Target: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Andere Bezeichnung: NDUFS1 (NDUFS1 Produkte)

Synonyme: 5830412M15Rik antikoerper, 9930026A05Rik antikoerper, CI-75Kd antikoerper, CI-75k antikoerper, PRO1304 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antikoerper, NADH:ubiquinone oxidoreductase core subunit S1 antikoerper, Ndufs1 antikoerper, NDUFS1 antikoerper

Hintergrund: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency.
Alias Symbols: CI-75Kd, MGC26839, PRO1304, CI-75k
Protein Interaction Partner: SUMO2, HSFY1, UBC, MDM2, RNF2, KDM1A, FBXO6, VCAM1, BTK, Htt, NDUFS7, RHOT2, NDUFA12, TMEM126B, MRPL13, STX12, SEC24C, SDHB, RPL27, RAB5B, OPA1, NDUFV3, NDUFV2, NDUFS8, NDUFV1, NDUFS2, NDUFB10, NDUFB9, NDUFB5, NDUFA9, CPT1A, ATP5C1, ATP5B, CUL3, SIRT7, MY
Protein Size: 727

Molekulargewicht: 77 kDa

Gen-ID: 4719

NCBI Accession: NM_005006, NP_004997

UniProt: P28331