PSMB4 Antikörper (Middle Region)
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- Target Alle PSMB4 Antikörper anzeigen
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PSMB4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SRRSKMNPLW NTMVIGGYAD GESFLGYVDM LGVAYEAPSL ATGYGAYLAQ
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PSMB4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PSMB4
- Top Product
- Discover our top product PSMB4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 264 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
- Andere Bezeichnung
- PSMB4 (PSMB4 Produkte)
- Synonyme
- An18g06680 antikoerper, PSMB4 antikoerper, Pros-27 antikoerper, HN3 antikoerper, HsN3 antikoerper, PROS-26 antikoerper, PROS26 antikoerper, im:6909492 antikoerper, zgc:110330 antikoerper, proteasome subunit beta type-4 antikoerper, proteasome subunit beta 4 antikoerper, proteasome (prosome, macropain) subunit, beta type 4 antikoerper, proteasome subunit beta 4 L homeolog antikoerper, ANI_1_890164 antikoerper, PSMB4 antikoerper, psmb4 antikoerper, Psmb4 antikoerper, psmb4.L antikoerper
- Hintergrund
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HN3, HsN3, PROS26, PROS-26
Protein Interaction Partner: FSD2, UBC, PSMA3, PSMD14, PSMD9, PSMC5, PSMA5, HNRNPA1, PSMG3, POMP, RPP38, PSMB8, PSMB7, PSMB6, PSMB5, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA4, PSMA1, KIF5B, HNRNPA2B1, EPB41L1, DDB2, PSMA2, PARK2, BAG3, PRKCA, SMAD1, CFTR, IQCB1, SULT1A4, PSMA8, SYAP1,
Protein Size: 264 - Molekulargewicht
- 29 kDa
- Gen-ID
- 5692
- NCBI Accession
- NM_002796, NP_002787
- UniProt
- P28070
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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