MIF Antikörper (Middle Region)

Produktnummer ABIN2786654

Produktdetails anti-MIF Antikörper

Target: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schaf, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PQYIAVHVVP DQLMAFGGSS EPCALCSLHS IGKIGGAQNR SYSKLLCGLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against MIF. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MIF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 115 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MIF

Target: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Andere Bezeichnung: MIF (MIF Produkte)

Synonyme: mif antikoerper, Mif antikoerper, gif antikoerper, glif antikoerper, mmif antikoerper, LOC100136498 antikoerper, LOC100284350 antikoerper, LOC100284546 antikoerper, GIF antikoerper, Glif antikoerper, GLIF antikoerper, MMIF antikoerper, macrophage migration inhibitory factor L homeolog antikoerper, macrophage migration inhibitory factor antikoerper, macrophage migration inhibitory factor (glycosylation-inhibiting factor) antikoerper, mif.L antikoerper, mif antikoerper, MIF antikoerper, Mif antikoerper, PHATRDRAFT_49660 antikoerper, LOC100136498 antikoerper, cl405_1 antikoerper, LOC100284546 antikoerper

Hintergrund: This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Alias Symbols: GIF, GLIF, MMIF
Protein Interaction Partner: WDYHV1, UBC, MIF, MDM2, ASB15, ZNF408, UPF2, BNIPL, HCVgp1, NGFRAP1, VCAM1, ITGA4, FN1, IGBP1, CLNS1A, COPS5, TP53, NME1, CDK2, STUB1, HSP90AA1, VHL, STRN4, COPS6, GORASP2, CD74, FIBP,
Protein Size: 115

Molekulargewicht: 12 kDa

Gen-ID: 4282

NCBI Accession: NM_002415, NP_002406

UniProt: P14174

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling