PPP2R2D Antikörper (C-Term)

Produktnummer ABIN2786544

Produktdetails anti-PPP2R2D Antikörper

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRDVTLEASR ENSKPRASLK PRKVCTGGKR KKDEISVDSL DFNKKILHTA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Ppp2r2d. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 453 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPP2R2D

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Andere Bezeichnung: Ppp2r2d (PPP2R2D Produkte)

Synonyme: 1300017E19Rik antikoerper, D7Ertd753e antikoerper, MDS026 antikoerper, protein phosphatase 2, regulatory subunit B, delta antikoerper, protein phosphatase 2 regulatory subunit Bdelta antikoerper, protein phosphatase 2 regulatory subunit B, delta S homeolog antikoerper, Ppp2r2d antikoerper, PPP2R2D antikoerper, ppp2r2d.S antikoerper

Hintergrund: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Alias Symbols: 1300017E19Rik, D7Ertd753e, MDS026
Protein Interaction Partner: Supt5, SMURF1, SMAD3, SMAD2,
Protein Size: 453

Molekulargewicht: 50 kDa

Gen-ID: 52432

NCBI Accession: NM_026391, NP_080667

UniProt: Q925E7