IARS Antikörper (Middle Region)

Produktnummer ABIN2785974

Produktdetails anti-IARS Antikörper

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IARS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1262 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IARS

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Andere Bezeichnung: IARS (IARS Produkte)

Synonyme: fi46h05 antikoerper, zgc:63790 antikoerper, wu:fi46h05 antikoerper, K19E20.18 antikoerper, K19E20_18 antikoerper, ovule abortion 2 antikoerper, ECK0027 antikoerper, ilvS antikoerper, JW0024 antikoerper, An08g06770 antikoerper, AO090012000505 antikoerper, 2510016L12Rik antikoerper, AI327140 antikoerper, AU044614 antikoerper, E430001P04Rik antikoerper, ILRS antikoerper, Iarsl antikoerper, IARS1 antikoerper, ILERS antikoerper, IRS antikoerper, PRO0785 antikoerper, isoleucyl-tRNA synthetase antikoerper, tRNA synthetase class I (I, L, M and V) family protein antikoerper, isoleucine--tRNA ligase antikoerper, isoleucyl-tRNA synthetase, cytoplasmic antikoerper, isoleucine-tRNA synthetase antikoerper, iars antikoerper, IARS antikoerper, OVA2 antikoerper, ileS antikoerper, MBAR_RS19160 antikoerper, Rmag_0340 antikoerper, ANI_1_964074 antikoerper, CHLREDRAFT_106327 antikoerper, EDI_049880 antikoerper, OE_RS08520 antikoerper, AOR_1_1912194 antikoerper, Iars antikoerper

Hintergrund: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: UBC, MDM2, SART3, AURKA, SUMO2, SUMO3, STAU1, LGR4, AIMP2, RPLP0, RPL38, RPL24, RPL23A, RPL18, RPL15, QARS, NMT1, MARS, MAP4, HNRNPA2B1, EPRS, DARS, AIMP1, HNRNPUL2, LARS, RPS27L, IGF2BP3, SYNCRIP, EEF1E1, FBXO6, EGFR, UBD, ITGA4, FN1, METTL18, gag, VCAM1
Protein Size: 1262

Molekulargewicht: 144 kDa

Gen-ID: 3376

NCBI Accession: NM_013417, NP_038203

UniProt: P41252