FES Antikörper (N-Term)

Produktnummer ABIN311723

Produktdetails anti-FES Antikörper

Target: FES (Feline Sarcoma Oncogene (FES))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Schwein, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FES Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ARDSAQAKRK YQEASKDKDR DKAKDKYVRS LWKLFAHHNR YVLGVRAAQL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 88%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FES. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FES

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 822 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FES

Target: FES (Feline Sarcoma Oncogene (FES))

Andere Bezeichnung: FES (FES Produkte)

Synonyme: FPS antikoerper, RGD1564385 antikoerper, AI586313 antikoerper, BB137047 antikoerper, c-fes antikoerper, FES antikoerper, c-fps antikoerper, FES proto-oncogene, tyrosine kinase antikoerper, feline sarcoma oncogene antikoerper, FES antikoerper, Fes antikoerper, fes antikoerper

Hintergrund: FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FPS
Protein Interaction Partner: MDFI, HSP90AA1, EGFR, UBC, TRIM28, POT1, TERF1, NEDD4, ZNF775, ZNF746, PDE4DIP, HSH2D, PLXNA1, DPYSL5, RASA3, BCAR1, DOK1, IRS2, JAK3, FES, PIK3R1, BCR, JAK2, JAK1, IL4R, IRS1, RASA1, CSF2RB, STAT3, PTGES3, PPID, HSPA4, FKBP5, FKBP4, PSMD13,
Protein Size: 822

Molekulargewicht: 93 kDa

Gen-ID: 2242

NCBI Accession: NM_002005, NP_001996

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2