FBXO31 Antikörper (Middle Region)

Produktnummer ABIN2785570

Produktdetails anti-FBXO31 Antikörper

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO31

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 367 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO31

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Andere Bezeichnung: FBXO31 (FBXO31 Produkte)

Synonyme: 1110003O08Rik antikoerper, 2310046N15Rik antikoerper, Fbx14 antikoerper, Fbxo14 antikoerper, FBX14 antikoerper, FBXO14 antikoerper, Fbx31 antikoerper, pp2386 antikoerper, RGD1561069 antikoerper, fbx14 antikoerper, fbx31 antikoerper, fbxo14 antikoerper, fbxo31 antikoerper, F-box protein 31 antikoerper, F-box protein 31 S homeolog antikoerper, F-box protein 31 L homeolog antikoerper, Fbxo31 antikoerper, FBXO31 antikoerper, fbxo31 antikoerper, fbxo31.S antikoerper, fbxo31.L antikoerper

Hintergrund: FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
Protein Size: 367

Molekulargewicht: 40 kDa

Gen-ID: 79791

NCBI Accession: NM_024735, NP_079011

UniProt: Q5XUX0