FBXO39 Antikörper (Middle Region)

Produktnummer ABIN503437

Produktdetails anti-FBXO39 Antikörper

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RQCALRVFKA RIYTNRYETN EEDKTLQEIY RKYRKLIESE LSYFVIVYSV

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO39. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO39

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 442 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO39

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Andere Bezeichnung: FBXO39 (FBXO39 Produkte)

Synonyme: Fbx39 antikoerper, 1700010H23Rik antikoerper, F-box protein 39 antikoerper, FBXO39 antikoerper, Fbxo39 antikoerper

Hintergrund: FBXO39 is the substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO39, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx39, MGC35179
Protein Size: 442

Molekulargewicht: 53 kDa

Gen-ID: 162517

NCBI Accession: NM_153230, NP_694962

UniProt: Q8N4B4