ASZ1 Antikörper (Middle Region)

Produktnummer ABIN2784974

Produktdetails anti-ASZ1 Antikörper

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASZ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GKMPSEIAKR NKHHEIFNLL SFTLNPLEGK LQQLTKEDTI CKILTTDSDR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ASZ1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASZ1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ASZ1

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Andere Bezeichnung: ASZ1 (ASZ1 Produkte)

Synonyme: Gasz antikoerper, GASZ antikoerper, gasz antikoerper, MGC56332 antikoerper, zgc:56332 antikoerper, ALP1 antikoerper, ANKL1 antikoerper, C7orf7 antikoerper, CT1.19 antikoerper, Orf3 antikoerper, 4933400N19Rik antikoerper, ORF3 antikoerper, ankyrin repeat, SAM and basic leucine zipper domain containing 1 antikoerper, Asz1 antikoerper, ASZ1 antikoerper, asz1 antikoerper

Hintergrund: ASZ1 plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity.ASZ1 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.ASZ1 is required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons.ASZ1 may act by mediating protein-protein interactions during germ cell maturation.
Alias Symbols: ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19
Protein Interaction Partner: TSG101,
Protein Size: 475

Molekulargewicht: 53 kDa

Gen-ID: 136991

NCBI Accession: NM_130768, NP_570124

UniProt: Q8WWH4