TNFRSF21 Antikörper (N-Term)

Produktnummer ABIN2782812

Produktdetails anti-TNFRSF21 Antikörper

Target: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TTTAQPEQKA SNLIGTYRHV DRATGQVLTC DKCPAGTYVS EHCTNTSLRV

Homologie: Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFRSF21. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 655 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFRSF21

Target: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Andere Bezeichnung: TNFRSF21 (TNFRSF21 Produkte)

Synonyme: TNFRSF21 antikoerper, tnfrsf21 antikoerper, MGC146356 antikoerper, BM-018 antikoerper, CD358 antikoerper, DR6 antikoerper, AA959878 antikoerper, R74815 antikoerper, TR7 antikoerper, dr6 antikoerper, im:6795346 antikoerper, wu:fa55e01 antikoerper, wu:fb02e11 antikoerper, wu:fc29a09 antikoerper, wu:fi27h08 antikoerper, TNF receptor superfamily member 21 antikoerper, tumor necrosis factor receptor superfamily member 21 antikoerper, tumor necrosis factor receptor superfamily, member 21 antikoerper, TNFRSF21 antikoerper, tnfrsf21 antikoerper, Tnfrsf21 antikoerper

Hintergrund: TNFRSF21 is a member of the TNF-receptor superfamily. This receptor has been shown to activate!!NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of!!TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Alias Symbols: BM-018, DR6, MGC31965, CD358
Protein Interaction Partner: NSD1, CLIP3, ELAVL1, WASH2P, MATR3, STX11, TRADD,
Protein Size: 655

Molekulargewicht: 68 kDa

Gen-ID: 27242

NCBI Accession: NM_014452, NP_055267

UniProt: O75509

Pathways: Regulation of Lipid Metabolism by PPARalpha