PRIM1 Antikörper (N-Term)

Produktnummer ABIN310748

Produktdetails anti-PRIM1 Antikörper

Target: PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SQYYRWLNYG GVIKNYFQHR EFSFTLKDDI YIRYQSFNNQ SDLEKEMQKM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PRIM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRIM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 420 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRIM1

Target: PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))

Andere Bezeichnung: PRIM1 (PRIM1 Produkte)

Synonyme: AI324982 antikoerper, p49 antikoerper, dnapol-alpha50 antikoerper, DNA primase, p49 subunit antikoerper, DNA primase subunit 1 antikoerper, DNA primase subunit 1 S homeolog antikoerper, Prim1 antikoerper, PRIM1 antikoerper, prim1.S antikoerper

Hintergrund: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. PRIM1 is the small, 49 kDa primase subunit.The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
Alias Symbols: MGC12308, p49
Protein Interaction Partner: FAM96B, CIAO1, UBC, MMS19, MDC1, POLA2, PRIM2, POLE, POLA1, COPS6, RPA3, RPA2, RPA1, RAE1, MRPL38, TP53, XRCC5,
Protein Size: 420

Molekulargewicht: 50 kDa

Gen-ID: 5557

NCBI Accession: NM_000946, NP_000937

UniProt: P49642

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interaktom