RORA Antikörper (N-Term)

Produktnummer ABIN2782302

Produktdetails anti-RORA Antikörper

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MESAPAAPDP AASEPGSSGS EAAAGSRETP LTQDTGRKSE APGAGRRQSY

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rora. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rora

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 523 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RORA

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Andere Bezeichnung: Rora (RORA Produkte)

Synonyme: ror1 antikoerper, ror2 antikoerper, ror3 antikoerper, rzra antikoerper, nr1f1 antikoerper, MGC146531 antikoerper, NR1F1 antikoerper, ROR1 antikoerper, ROR2 antikoerper, ROR3 antikoerper, RZR-ALPHA antikoerper, RZRA antikoerper, RORalpha-B antikoerper, gb:dq017624 antikoerper, rora2 antikoerper, 9530021D13Rik antikoerper, Nr1f1 antikoerper, nmf267 antikoerper, sg antikoerper, staggerer antikoerper, tmgc26 antikoerper, RORalpha1 antikoerper, RAR related orphan receptor A antikoerper, RAR-related orphan receptor A antikoerper, RAR-related orphan receptor A, paralog a antikoerper, RAR-related orphan receptor alpha antikoerper, RORA antikoerper, rora antikoerper, Rora antikoerper, roraa antikoerper

Hintergrund: Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives.
Alias Symbols: 9530021D13Rik, Nr1f1, ROR1, ROR2, ROR3, nmf267, sg, staggerer, tmgc26
Protein Interaction Partner: Atxn1,
Protein Size: 523

Molekulargewicht: 59 kDa

Gen-ID: 19883

NCBI Accession: NM_013646, NP_038674

UniProt: P51448

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha