TGFBR2 Antikörper (N-Term)
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- Target Alle TGFBR2 Antikörper anzeigen
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schwein, Schaf, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TGFBR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MGRGLLRGLW PLHIVLWTRI ASTIPPHVQK SDVEMEAQKD EIICPSCNRT
- Homologie
- Cow: 93%, Goat: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TGFBR2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TGFBR2
- Top Product
- Discover our top product TGFBR2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 567 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
- Andere Bezeichnung
- TGFBR2 (TGFBR2 Produkte)
- Synonyme
- AAT3 antikoerper, FAA3 antikoerper, LDS1B antikoerper, LDS2B antikoerper, MFS2 antikoerper, RIIC antikoerper, TAAD2 antikoerper, TGFR-2 antikoerper, TGFbeta-RII antikoerper, 1110020H15Rik antikoerper, AU042018 antikoerper, DNIIR antikoerper, RIIDN antikoerper, TBR-II antikoerper, TbetaR-II antikoerper, TbetaRII antikoerper, TGFBR2 antikoerper, TBETA-RII antikoerper, TGFBRII antikoerper, TGF-beta 2 antikoerper, Tgfbr2T antikoerper, cb537 antikoerper, tgfbr2 antikoerper, wu:fj05c10 antikoerper, zgc:110498 antikoerper, transforming growth factor beta receptor 2 antikoerper, transforming growth factor, beta receptor II antikoerper, transforming growth factor, beta receptor 2 antikoerper, transforming growth factor beta receptor 2b antikoerper, TGFBR2 antikoerper, Tgfbr2 antikoerper, tgfbr2b antikoerper
- Hintergrund
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TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in its gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.This gene is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It encodes a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein and binds TGF-beta. This receptor/ligand complex phosphorylates proteins which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: HNPCC6, MFS2, RIIC, Tbeta, AAT3, FAA3, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII
Protein Interaction Partner: TRAF4, NRP1, NRP2, TGFB1, TERT, PEG10, ENG, GOPC, IQGAP1, UBC, RCVRN, PDGFRA, APP, TGFBR1, MAP3K7, PAK1, OCLN, SMAD7, CDC42, Hsp90aa1, KCNK18, FBXO34, PPP1R16B, OXSR1, ARHGEF6, TRAF6, TSC22D1, SMURF1, OSR1, TCTEX1D4, SNX6, TSSK1B, TGFBRAP1, TRAP1, STRAP,
Protein Size: 567 - Molekulargewicht
- 62 kDa
- Gen-ID
- 7048
- NCBI Accession
- NM_003242, NP_003233
- UniProt
- P37173
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