CYBB Antikörper (C-Term)
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- Target Alle CYBB Antikörper anzeigen
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYBB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- YGRPNWDNEF KTIASQHPNT RIGVFLCGPE ALAETLSKQS ISNSESGPRG
- Homologie
- Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYBB. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CY24B
- Top Product
- Discover our top product CYBB Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 570 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
- Andere Bezeichnung
- CYBB (CYBB Produkte)
- Synonyme
- zgc:64144 antikoerper, cgd antikoerper, gp91-1 antikoerper, gp91-phox antikoerper, gp91phox antikoerper, nox2 antikoerper, NOX2 antikoerper, cybb antikoerper, NOX1 antikoerper, AMCBX2 antikoerper, CGD antikoerper, GP91-1 antikoerper, GP91-PHOX antikoerper, GP91PHOX antikoerper, p91-PHOX antikoerper, Nox2 antikoerper, C88302 antikoerper, CGD91-phox antikoerper, Cgd antikoerper, Cyd antikoerper, Gp91-phox antikoerper, CYBB antikoerper, cytochrome b-245, beta polypeptide (chronic granulomatous disease) antikoerper, cytochrome b-245, beta polypeptide antikoerper, cytochrome b-245 heavy chain antikoerper, cytochrome b-245, beta polypeptide L homeolog antikoerper, cytochrome b-245 beta polypeptide antikoerper, cytochrome b-245 beta chain antikoerper, NADPH oxidase heavy chain subunit antikoerper, cybb antikoerper, CYBB antikoerper, cybb.L antikoerper, Cybb antikoerper, GP91-PHOX antikoerper
- Hintergrund
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Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Alias Symbols: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX,
Protein Interaction Partner: IQGAP1, ACTB, UBC, SUMO1, RAC1, NCF4, NCF2, NCF1, CYBA, ACTG1,
Protein Size: 570 - Molekulargewicht
- 62 kDa
- Gen-ID
- 1536
- NCBI Accession
- NM_000397, NP_000388
- UniProt
- P04839
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