ACVRL1 Antikörper (N-Term)
-
- Target Alle ACVRL1 Antikörper anzeigen
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Maus, Ratte, Hund, Schwein, Pferd
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ACVRL1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- SPHCKGPTCR GAWCTVVLVR EEGRHPQEHR GCGNLHRELC RGRPTEFVNH
- Homologie
- Dog: 100%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ACVRL1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVRL1
- Top Product
- Discover our top product ACVRL1 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 503 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Andere Bezeichnung
- ACVRL1 (ACVRL1 Produkte)
- Synonyme
- ACVRL1 antikoerper, vgb antikoerper, alk1 antikoerper, zehn1109 antikoerper, hm:zehn1109 antikoerper, ACVRLK1 antikoerper, ALK-1 antikoerper, ALK1 antikoerper, HHT antikoerper, HHT2 antikoerper, ORW2 antikoerper, SKR3 antikoerper, TSR-I antikoerper, R-3 antikoerper, R3 antikoerper, SETHKIR antikoerper, AI115505 antikoerper, AI427544 antikoerper, Acvrlk1 antikoerper, Alk1 antikoerper, activin A receptor like type 1 antikoerper, activin A receptor type II-like 1 antikoerper, activin A receptor, type II-like 1 antikoerper, ACVRL1 antikoerper, acvrl1 antikoerper, Acvrl1 antikoerper
- Hintergrund
-
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: TGFBR1, TGFB1, INHBA, SMAD1, PEG10, NR1H2, FKBP1A, CSNK2B, ENG, BAMBI, HSP90AA1, IGSF1, TSC22D1, SNX6, TGFBRAP1, XIAP, TGFB3, TGFBR2, ACVR2A,
Protein Size: 503 - Molekulargewicht
- 55 kDa
- Gen-ID
- 94
- NCBI Accession
- NM_000020, NP_000011
- UniProt
- P37023
-