SLC8A3 Antikörper (N-Term)

Produktnummer ABIN2781702

Produktdetails anti-SLC8A3 Antikörper

Target: SLC8A3 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC8A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SAPEILLSLI EVCGHGFIAG DLGPSTIVGS AAFNMFIIIG ICVYVIPDGE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC8A3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC8A3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 925 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC8A3 Antikörper (ABIN2781702)

Heise, Shumilina, Nurbaeva, Schmid, Szteyn, Yang, Xuan, Wang, Zemtsova, Duszenko, Lang: "Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells." in: American journal of physiology. Cell physiology, Vol. 300, Issue 6, pp. C1306-13, (2011) (PubMed).

Details zu SLC8A3

Target: SLC8A3 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3))

Andere Bezeichnung: SLC8A3 (SLC8A3 Produkte)

Synonyme: SLC8A3 antikoerper, NCX3 antikoerper, Ncx3 antikoerper, AW742262 antikoerper, solute carrier family 8 member A3 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 3 antikoerper, SLC8A3 antikoerper, slc8a3 antikoerper, Slc8a3 antikoerper

Hintergrund: SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner.This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Alias Symbols: NCX3
Protein Interaction Partner: YWHAE, YWHAB, YWHAQ, PPP3CB,
Protein Size: 925

Molekulargewicht: 103 kDa

Gen-ID: 6547

NCBI Accession: NM_033262, NP_150287

UniProt: Q96QG2