NSMCE1 Antikörper (Middle Region)

Produktnummer ABIN2781252

Produktdetails anti-NSMCE1 Antikörper

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Kaninchen, Rind (Kuh), Ziege, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSMCE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KKEAEQVLQK FVQNKWLIEK EGEFTLHGRA ILEMEQYIRE TYPDAVKICN

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NSMCE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 266 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NSMCE1

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Andere Bezeichnung: NSMCE1 (NSMCE1 Produkte)

Synonyme: zgc:92777 antikoerper, NSMCE1 antikoerper, NSE1 antikoerper, 2510027N19Rik antikoerper, RGD1307760 antikoerper, NSE1 homolog, SMC5-SMC6 complex component antikoerper, NSE1 homolog, SMC5-SMC6 complex component L homeolog antikoerper, nsmce1 antikoerper, NSMCE1 antikoerper, nsmce1.L antikoerper, Nsmce1 antikoerper

Hintergrund: NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: NSE1
Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
Protein Size: 266

Molekulargewicht: 31 kDa

Gen-ID: 197370

NCBI Accession: NM_145080, NP_659547

UniProt: Q8WV22

Pathways: Positive Regulation of Response to DNA Damage Stimulus