Coronin 1a Antikörper (C-Term)

Produktnummer ABIN2780827

Produktdetails anti-Coronin 1a Antikörper

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coronin 1a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELRVNRGLDT GRRRAAPEAS GTPSSDAVSR LEEEMRKLQA TVQELQKRLD

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 90%, Rabbit: 79%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against CORO1A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CORO1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 461 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Coronin 1a

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Andere Bezeichnung: CORO1A (CORO1A Produkte)

Synonyme: CORO1A antikoerper, cor1a antikoerper, Clabp antikoerper, Lmb3 antikoerper, TACO antikoerper, p57 antikoerper, CLABP antikoerper, CLIPINA antikoerper, HCORO1 antikoerper, fj83g12 antikoerper, wu:fj83g12 antikoerper, zgc:63766 antikoerper, coronin 1A antikoerper, Coronin-1A antikoerper, coronin, actin binding protein 1A antikoerper, coronin, actin binding protein, 1A antikoerper, CORO1A antikoerper, cor1a antikoerper, Coro1a antikoerper, coro1a antikoerper

Hintergrund: CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
Alias Symbols: p57, TACO, CLABP, HCORO1, CLIPINA
Protein Interaction Partner: FSD2, GOLGA2, UBC, YTHDC1, SPATA20, POT1, TAB1, GIT2, POLR1C, STAT3, SMARCD1, MAGOH, SMAD3, LMO2, FHL3, FMNL1, NCF4, THBS1, ACTB, DKK1, UBE2G2,
Protein Size: 461

Molekulargewicht: 51 kDa

Gen-ID: 11151

NCBI Accession: NM_007074, NP_009005

UniProt: Q2YD73

Pathways: Regulation of Actin Filament Polymerization