NR1D2 Antikörper (N-Term)
-
- Target Alle NR1D2 Antikörper anzeigen
- NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NR1D2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- YISSSSSASS HASCHSEGSE NSFQSSSSSV PSSPNSSNSD TNGNPKNGDL
- Homologie
- Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NR1D2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR1D2
- Top Product
- Discover our top product NR1D2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 579 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
- Andere Bezeichnung
- NR1D2 (NR1D2 Produkte)
- Synonyme
- BD73 antikoerper, EAR-1R antikoerper, RVR antikoerper, HZF-2 antikoerper, Rev-erb antikoerper, REV-ERBB antikoerper, NR1D2 antikoerper, rvr antikoerper, bd73 antikoerper, hzf2 antikoerper, ear-1r antikoerper, hs.37288 antikoerper, NR1D2-A antikoerper, Reverbbeta-A antikoerper, reverbb1 antikoerper, reverbb antikoerper, reverbb2 antikoerper, zgc:92019 antikoerper, nuclear receptor subfamily 1 group D member 2 antikoerper, nuclear receptor subfamily 1, group D, member 2 antikoerper, nuclear receptor subfamily 1, group D, member 2a antikoerper, nuclear receptor subfamily 1, group D, member 2b antikoerper, NR1D2 antikoerper, Nr1d2 antikoerper, nr1d2 antikoerper, nr1d2a antikoerper, nr1d2b antikoerper
- Hintergrund
-
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Alias Symbols: BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
Protein Interaction Partner: MID2, RBPMS, TRIM27, NOTCH2NL, KRTAP10-9, KRT40, KRTAP4-2, PRMT6, SKP1, UBC, SIN3B, KAT5, NCOR1, TAF9, TAF6, HDAC1, GTF2B, NCOA5, UBE2I, CUL1, NR1D1, RGN,
Protein Size: 579 - Molekulargewicht
- 65 kDa
- Gen-ID
- 9975
- NCBI Accession
- NM_005126, NP_005117
- UniProt
- Q14995
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
-